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Atlantic sturgeon were fished almost to extinction − ancient DNA reveals how Chesapeake Bay population changed over centuries

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theconversation.com – Natalia Przelomska, Research Associate in Archaeogenomics, National Museum of Natural History, Smithsonian Institution – 2025-03-20 07:47:00

Sturgeon can be several hundred pounds each.
cezars/E+ via Getty Images

Natalia Przelomska, Smithsonian Institution and Logan Kistler, Smithsonian Institution

Sturgeons are one of the oldest groups of fishes. Sporting an armor of five rows of bony, modified scales called dermal scutes and a sharklike tail fin, this group of several-hundred-pound beasts has survived for approximately 160 million years. Because their physical appearance has changed very little over time, supported by a slow rate of evolution, sturgeon have been called living fossils.

Despite their survival through several geological time periods, many present-day sturgeon species are at threat of extinction, with 17 of 27 species listed as “critically endangered.”

Conservation practitioners such as the Virginia Commonwealth University monitoring team are working hard to support recovery of Atlantic sturgeon in the Chesapeake Bay area. But it’s not clear what baseline population level people should strive toward restoring. How do today’s sturgeon populations compare with those of the past?

Three people carefully lower a large fish over the side of a boat toward the water
VCU monitoring team releases an adult Atlantic sturgeon back into the estuary.
Matt Balazik

We are a molecular anthropologist and a biodiversity scientist who focus on species that people rely on for subsistence. We study the evolution, population health and resilience of these species over time to better understand humans’ interaction with their environments and the sustainability of food systems.

For our recent sturgeon project, we joined forces with fisheries conservation biologist Matt Balazik, who conducts on-the-ground monitoring of Atlantic sturgeon, and Torben Rick, a specialist in North American coastal zooarchaeology. Together, we wanted to look into the past and see how much sturgeon populations have changed, focusing on the James River in Virginia. A more nuanced understanding of the past could help conservationists better plan for the future.

Sturgeon loomed large for millennia

In North America, sturgeon have played important subsistence and cultural roles in Native communities, which marked the seasons by the fishes’ behavioral patterns. Large summertime aggregations of lake sturgeon (Acipenser fulvescens) in the Great Lakes area inspired one folk name for the August full moon – the sturgeon moon. Woodland Era pottery remnants at archaeological sites from as long as 2,000 years ago show that the fall and springtime runs of Atlantic sturgeon (Acipenser oxyrinchus) upstream were celebrated with feasting.

triangular-shaped bone with round cavities
Archaeologists uncover bony scutes – modified scales that resemble armor for the living fish – in places where people relied on sturgeon for subsistence.
Logan Kistler and Natalia Przelomska

Archaeological finds of sturgeon remains support that early colonial settlers in North America, notably those who established Jamestown in the Chesapeake Bay area in 1607, also prized these fish. When Captain John Smith was leading Jamestown, he wrote “there was more sturgeon here than could be devoured by dog or man.” The fish may have helped the survival of this fortress-colony that was both stricken with drought and fostering turbulent relationships with the Native inhabitants.

This abundance is in stark contrast to today, when sightings of migrating fish are sparse. Exploitation during the past 300 years was the key driver of Atlantic sturgeon decline. Demand for caviar drove the relentless fishing pressure throughout the 19th century. The Chesapeake was the second-most exploited sturgeon fishery on the Eastern Seaboard up until the early 20th century, when the fish became scarce.

Man pulls large fish over side of boat
Conservation biologists capture the massive fish for monitoring purposes, which includes clipping a tiny part of the fin for DNA analysis.
Matt Balazik

At that point, local protection regulations were established, but only in 1998 was a moratorium on harvesting these fish declared. Meanwhile, abundance of Atlantic sturgeon remained very low, which can be explained in part by their lifespan. Short-lived fish such as herring and shad can recover population numbers much faster than Atlantic sturgeon, which live for up to 60 years and take a long time to reach reproductive age – up to around 12 years for males and as many as 28 years for females.

To help manage and restore an endangered species, conservation biologists tend to split the population into groups based on ranges. The Chesapeake Bay is one of five “distinct population segments” the U.S. Endangered Species Act listing in 2012 created for Atlantic sturgeon.

Since then, conservationists have pioneered genetic studies on Atlantic sturgeon, demonstrating through the power of DNA that natal river – where an individual fish is born – and season of spawning are both important for distinguishing subpopulations within each regional group. Scientists have also described genetic diversity in Atlantic sturgeon; more genetic variety suggests they have more capacity to adapt when facing new, potentially challenging conditions.

map highlighting Maycock's Point, Hatch Site, Jamestown and Williamsburg on the James River
The study focused on Atlantic sturgeon from the Chesapeake Bay region, past and present. The four archaeological sites included are highlighted.
Przelomska NAS et al., Proc. R. Soc. B 291: 20241145, CC BY

Sturgeon DNA, then and now

Archaeological remains are a direct source of data on genetic diversity in the past. We can analyze the genetic makeup of sturgeons that lived hundreds of years ago, before intense overfishing depleted their numbers. Then we can compare that baseline with today’s genetic diversity.

The James River was a great case study for testing out this approach, which we call an archaeogenomics time series. Having obtained information on the archaeology of the Chesapeake region from our collaborator Leslie Reeder-Myers, we sampled remains of sturgeon – their scutes and spines – at a precolonial-era site where people lived from about 200 C.E. to about 900 C.E. We also sampled from important colonial sites Jamestown (1607-1610) and Williamsburg (1720-1775). And we complemented that data from the past with tiny clips from the fins of present-day, live fish that Balazik and his team sampled during monitoring surveys.

scattering of small bone shards spilling out of ziplock bag, with a purple-gloved hand
Scientists separate Atlantic sturgeon scute fragments from larger collections of zooarchaeological remains, to then work on the scutes in a lab dedicated to studying ancient DNA.
Torben Rick and Natalia Przelomska

DNA tends to get physically broken up and biochemically damaged with age. So we relied on special protocols in a lab dedicated to studying ancient DNA to minimize the risk of contamination and enhance our chances of successfully collecting genetic material from these sturgeon.

Atlantic sturgeon have 122 chromosomes of nuclear DNA – over five times as many as people do. We focused on a few genetic regions, just enough to get an idea of the James River population groupings and how genetically distinct they are from one another.

We were not surprised to see that fall-spawning and spring-spawning groups were genetically distinct. What stood out, though, was how starkly different they were, which is something that can happen when a population’s numbers drop to near-extinction levels.

We also looked at the fishes’ mitochondrial DNA, a compact molecule that is easier to obtain ancient DNA from compared with the nuclear chromosomes. With our collaborator Audrey Lin, we used the mitochondrial DNA to confirm our hypothesis that the fish from archaeological sites were more genetically diverse than present-day Atlantic sturgeon.

Strikingly, we discovered that mitochondrial DNA did not always group the fish by season or even by their natal river. This was unexpected, because Atlantic sturgeon tend to return to their natal rivers for breeding. Our interpretation of this genetic finding is that over very long timescales – many thousands of years – changes in the global climate and in local ecosystems would have driven a given sturgeon population to migrate into a new river system, and possibly at a later stage back to its original one. This notion is supported by other recent documentation of fish occasionally migrating over long distances and mixing with new groups.

Our study used archaeology, history and ecology together to describe the decline of Atlantic sturgeon. Based on the diminished genetic diversity we measured, we estimate that the Atlantic sturgeon populations we studied are about a fifth of what they were before colonial settlement. Less genetic variability means these smaller populations have less potential to adapt to changing conditions. Our findings will help conservationists plan into the future for the continued recovery of these living fossils.The Conversation

Natalia Przelomska, Research Associate in Archaeogenomics, National Museum of Natural History, Smithsonian Institution and Logan Kistler, Curator of Archaeobotany and Archaeogenomics, National Museum of Natural History, Smithsonian Institution

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Scientists found a potential sign of life on a distant planet – an astronomer explains why many are still skeptical

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theconversation.com – Daniel Apai, Associate Dean for Research and Professor of Astronomy and Planetary Sciences, University of Arizona – 2025-04-18 17:44:00

An illustration of the exoplanet K2-18b, which some research suggests may be covered by deep oceans.
NASA, ESA, CSA, Joseph Olmsted (STScI)

Daniel Apai, University of Arizona

A team of astronomers announced on April 16, 2025, that in the process of studying a planet around another star, they had found evidence for an unexpected atmospheric gas. On Earth, that gas – called dimethyl sulfide – is mostly produced by living organisms.

In April 2024, the James Webb Space Telescope stared at the host star of the planet K2-18b for nearly six hours. During that time, the orbiting planet passed in front of the star. Starlight filtered through its atmosphere, carrying the fingerprints of atmospheric molecules to the telescope.

A diagram showing planets and stars emitting light, which goes through JWST detectors, where it's split into different wavelengths to make a spectrum. Each spectrum suggests the presence of a different element.
JWST’s cameras can detect molecules in the atmosphere of a planet by looking at light that passed through that atmosphere.
European Space Agency

By comparing those fingerprints to 20 different molecules that they would potentially expect to observe in the atmosphere, the astronomers concluded that the most probable match was a gas that, on Earth, is a good indicator of life.

I am an astronomer and astrobiologist who studies planets around other stars and their atmospheres. In my work, I try to understand which nearby planets may be suitable for life.

K2-18b, a mysterious world

To understand what this discovery means, let’s start with the bizarre world it was found in. The planet’s name is K2-18b, meaning it is the first planet in the 18th planetary system found by the extended NASA Kepler mission, K2. Astronomers assign the “b” label to the first planet in the system, not “a,” to avoid possible confusion with the star.

K2-18b is a little over 120 light-years from Earth – on a galactic scale, this world is practically in our backyard.

Although astronomers know very little about K2-18b, we do know that it is very unlike Earth. To start, it is about eight times more massive than Earth, and it has a volume that’s about 18 times larger. This means that it’s only about half as dense as Earth. In other words, it must have a lot of water, which isn’t very dense, or a very big atmosphere, which is even less dense.

Astronomers think that this world could either be a smaller version of our solar system’s ice giant Neptune, called a mini-Neptune, or perhaps a rocky planet with no water but a massive hydrogen atmosphere, called a gas dwarf.

Another option, as University of Cambridge astronomer Nikku Madhusudhan recently proposed, is that the planet is a “hycean world”.

That term means hydrogen-over-ocean, since astronomers predict that hycean worlds are planets with global oceans many times deeper than Earth’s oceans, and without any continents. These oceans are covered by massive hydrogen atmospheres that are thousands of miles high.

Astronomers do not know yet for certain that hycean worlds exist, but models for what those would look like match the limited data JWST and other telescopes have collected on K2-18b.

This is where the story becomes exciting. Mini-Neptunes and gas dwarfs are unlikely to be hospitable for life, because they probably don’t have liquid water, and their interior surfaces have enormous pressures. But a hycean planet would have a large and likely temperate ocean. So could the oceans of hycean worlds be habitable – or even inhabited?

Detecting DMS

In 2023, Madhusudhan and his colleagues used the James Webb Space Telescope’s short-wavelength infrared camera to inspect starlight that filtered through K2-18b’s atmosphere for the first time.

They found evidence for the presence of two simple carbon-bearing molecules – carbon monoxide and methane – and showed that the planet’s upper atmosphere lacked water vapor. This atmospheric composition supported, but did not prove, the idea that K2-18b could be a hycean world. In a hycean world, water would be trapped in the deeper and warmer atmosphere, closer to the oceans than the upper atmosphere probed by JWST observations.

Intriguingly, the data also showed an additional, very weak signal. The team found that this weak signal matched a gas called dimethyl sulfide, or DMS. On Earth, DMS is produced in large quantities by marine algae. It has very few, if any, nonbiological sources.

This signal made the initial detection exciting: on a planet that may have a massive ocean, there is likely a gas that is, on Earth, emitted by biological organisms.

An illustration of what scientists imagine K2-18b to look like, which looks a little like Earth, with clouds and a translucent surface.
K2-18b could have a deep ocean spanning the planet, and a hydrogen atmosphere.
Amanda Smith, Nikku Madhusudhan (University of Cambridge), CC BY-SA

Scientists had a mixed response to this initial announcement. While the findings were exciting, some astronomers pointed out that the DMS signal seen was weak and that the hycean nature of K2-18b is very uncertain.

To address these concerns, Mashusudhan’s team turned JWST back to K2-18b a year later. This time, they used another camera on JWST that looks for another range of wavelengths of light. The new results – announced on April 16, 2025 – supported their initial findings.

These new data show a stronger – but still relatively weak – signal that the team attributes to DMS or a very similar molecule. The fact that the DMS signal showed up on another camera during another set of observations made the interpretation of DMS in the atmosphere stronger.

Madhusudhan’s team also presented a very detailed analysis of the uncertainties in the data and interpretation. In real-life measurements, there are always some uncertainties. They found that these uncertainties are unlikely to account for the signal in the data, further supporting the DMS interpretation. As an astronomer, I find that analysis exciting.

Is life out there?

Does this mean that scientists have found life on another world? Perhaps – but we still cannot be sure.

First, does K2-18b really have an ocean deep beneath its thick atmosphere? Astronomers should test this.

Second, is the signal seen in two cameras two years apart really from dimethyl sulfide? Scientists will need more sensitive measurements and more observations of the planet’s atmosphere to be sure.

Third, if it is indeed DMS, does this mean that there is life? This may be the most difficult question to answer. Life itself is not detectable with existing technology. Astronomers will need to evaluate and exclude all other potential options to build their confidence in this possibility.

The new measurements may lead researchers toward a historic discovery. However, important uncertainties remain. Astrobiologists will need a much deeper understanding of K2-18b and similar worlds before they can be confident in the presence of DMS and its interpretation as a signature of life.

Scientists around the world are already scrutinizing the published study and will work on new tests of the findings, since independent verification is at the heart of science.

Moving forward, K2-18b is going to be an important target for JWST, the world’s most sensitive telescope. JWST may soon observe other potential hycean worlds to see if the signal appears in the atmospheres of those planets, too.

With more data, these tentative conclusions may not stand the test of time. But for now, just the prospect that astronomers may have detected gasses emitted by an alien ecosystem that bubbled up in a dark, blue-hued alien ocean is an incredibly fascinating possibility.

Regardless of the true nature of K2-18b, the new results show how using the JWST to survey other worlds for clues of alien life will guarantee that the next years will be thrilling for astrobiologists.The Conversation

Daniel Apai, Associate Dean for Research and Professor of Astronomy and Planetary Sciences, University of Arizona

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As views on spanking shift worldwide, most US adults support it, and 19 states allow physical punishment in schools

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theconversation.com – Christina Erickson, Associate Dean in the College of Nursing and Professional Disciplines, University of North Dakota – 2025-04-18 07:39:00

Spanking in the U.S. generally ends around age 12, when children become big enough to resist or fight back.
Sandro Di Carlo Darsa/Brand X Pictures via Getty Images

Christina Erickson, University of North Dakota

Nearly a half-century after the Supreme Court ruled that school spankings are permissible and not “cruel and unusual punishment”, many U.S. states allow physical punishment for students who have misbehaved.

Today, over a third of the states allow teachers to paddle or spank students. More than 100,000 students are paddled in U.S. schools each year.

Christina Erickson, an associate dean and professor of social work at the University of North Dakota, wrote a book on the subject: “Spanked: How Hitting Our Children is Harming Ourselves.” She discussed the scope of the practice and its effects with The Conversation.

What spanking legislation exists worldwide?

Around the world, 68 countries have banned the hitting of children in any form, including spanking. This movement began in 1979 with Sweden’s ban on all forms of physical punishment, including spanking in any setting, and including in the family home.

The pace of change quickened in the early 2000s when more countries adopted similar laws. For example, the legal language of countries like Nepal rests on an emerging definition of children as rights holders similar to adults and as humans worth protecting from harm.

Back view of students sitting at desks inside a classroom.
Spanking in schools is legal in 19 states.
Maskot/Getty Images

What are US policies toward spanking?

Each state in the U.S. has its own child abuse laws, and all states, tribes and territories aim to protect children from abuse. But all state laws also allow parents to hit their children if it does not leave an injury or a mark.

A typical example is Oklahoma’s definition of child abuse and neglect. It includes an exception that permits parents to use ordinary force as a means of discipline, including spanking, using an implement like a switch or a paddle. However, leaving evidence of hitting, such as welts, bruises, swelling or lacerations, is illegal and considered child abuse in all states.

Parental spanking of children is considered unique from other physical violence because of the relational context and the purpose. Laws entitle parents to hit their children for the purpose of teaching a lesson or punishing them to improve behavior. Children are the only individuals in society who can be hit by another person and the law does not regard it as assault.

Spanking’s impact on a child is unfortunately similar to abusive hitting. Spanking has been labeled as an “Adverse Childhood Experience,” or ACE. These are events that cause poor health outcomes over the span of one’s life.

The practice of spanking also affects parents. Acceptance of the physical discipline of spanking puts parents at risk for the escalation of physical punishment that leads to abuse.

Parents who spank their child have the potential to abuse them and be caught in a legal and child protection system that aims to protect children from harm. It is unclear what triggers a parent to cross over from discipline into abuse. Research shows that spanking at a young age, such as a 1-year-old, increases the chance of involvement by Child Protective Services by 33%.

Some school districts require permission from parents to allow disciplinary paddling in school, while others do not require any communication. State law does not assure agreement between parents and school districts on what offenses warrant a paddling. Parents may feel they have no alternative but to keep their child in school, or fear reprisal from school administrators. Some students are old enough to denounce the punishment themselves.

YouTube video
In this school district, physical punishment is used only when parents give written permission.

Is spanking considered the same as hitting?

The term spank conceals the concept of hitting and is so commonplace it goes unquestioned, despite the fact that it is a grown adult hitting a person much smaller than them. The concept is further concealed because hitting a child’s bottom hides any injuries that may occur.

Types of hitting that are categorized as spanking have narrowed over the years but still persist. Some parents still use implements such as tree switches, wooden spoons, shoes or paddles to “spank” children, raising the chances for abuse.

Most spanking ends by the age of 12, partly because children this age are able to fight back. When a child turns 18, parental hitting becomes the same as hitting any other adult, a form of domestic violence or assault throughout the U.S.

There is a lack of a consistent understanding of what constitutes a spanking. The definition of spanking is unique to each family. The number of hits, clothed or not, or using an implement, all reflect geographical or familial differences in understanding what a spanking is.

How do US adults view spanking?

People in the United States generally accept spanking as part of raising children: 56% of U.S. adults strongly agree or agree that “… it is sometimes necessary to discipline a child with a good, hard spanking.” This view has been slowly changing since 1986, when 83% of adults agreed with that statement.

The laws worldwide that protect children from being hit usually begin by disallowing nonparental adults to hit children. This is happening in the U.S. too, where 31 states have banned paddling in schools.

At a national level, efforts have been made to end physical punishment in schools. However, 19 states still allow spanking of children in public schools, which was upheld by a 1977 Supreme Court case.

With the slow but steady drop of parents who believe that sometimes children need a good hard spanking, as well as the ban of paddling in schools in 31 states, one could argue that the U.S. is moving toward a reduction in spanking.

What does research say about spanking?

Spanking’s negative influence on children’s behavior has been documented for decades. Spanking seems to work in the moment when it comes to changing or stopping the immediate behavior, but the negative effects are hidden in the short term and occur later in the child’s life. Yet because the spanking seemed to work at the time, the parent doesn’t connect the continued bad behavior of the child to the spanking.

An abundance of research shows that spanking causes increased negative behaviors in childhood. Spanking lowers executive functioning for children, increases dating violence as teenagers and even increases struggles with mental health and substance abuse in adulthood. Spanking does not teach new or healthy behaviors, and is a stress-inducing event for the child and the adult hitting them.

No studies have shown positive long-term benefits from spanking. Because of the long-standing and expansive research findings showing a range of harm from spanking and the increased association with child abuse, the American Psychological Association recommends that parents should never spank their children.

What are some resources for parents?

Consider these questions when choosing a discipline method for your child:

  • Is the expectation of your child developmentally accurate? One of the most common reasons parents spank is because they are expecting a behavior the child is not developmentally able to execute.

  • Can the discipline you choose grow with your child? Nearly all spanking ends by age 12, when kids are big enough to fight back. Choose discipline methods you can use over the long term, such as additional chores, apologies, difficult conversations and others that can grow with your child.

  • Might there be another explanation for your child’s behavior? Difficulty of understanding, fear or miscommunication? Think of your child as a learner and use a growth mindset to help your child learn from their life experiences.

Parents are the leaders of their families. Good leaders show strength in nonthreatening ways, listen to others and explain their decisions. Don’t spoil your kids. But being firm does not have to include hitting.

Is spanking children good for parents?

Doubtful. Parents who hit their kids may be unaware that it influences their frustration in other relationships. Expressing aggression recharges an angry and short-tempered internal battery that transfers into other parts of the adults’ lives.

Practicing calm when with your children will help you be calmer at work and in your other relationships. Listening to and speaking with a child about challenges, even from a very early age, is the best way to make it part of your relationship for the rest of your life.

Choose a method that allows you to grow. Parents matter too.The Conversation

Christina Erickson, Associate Dean in the College of Nursing and Professional Disciplines, University of North Dakota

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How does your brain create new memories? Neuroscientists discover ‘rules’ for how neurons encode new information

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theconversation.com – William Wright, Postdoctoral Scholar in Neurobiology, University of California, San Diego – 2025-04-17 13:00:00

Neurons that fire together sometimes wire together.
PASIEKA/Science Photo Library via Getty Images

William Wright, University of California, San Diego and Takaki Komiyama, University of California, San Diego

Every day, people are constantly learning and forming new memories. When you pick up a new hobby, try a recipe a friend recommended or read the latest world news, your brain stores many of these memories for years or decades.

But how does your brain achieve this incredible feat?

In our newly published research in the journal Science, we have identified some of the “rules” the brain uses to learn.

Learning in the brain

The human brain is made up of billions of nerve cells. These neurons conduct electrical pulses that carry information, much like how computers use binary code to carry data.

These electrical pulses are communicated with other neurons through connections between them called synapses. Individual neurons have branching extensions known as dendrites that can receive thousands of electrical inputs from other cells. Dendrites transmit these inputs to the main body of the neuron, where it then integrates all these signals to generate its own electrical pulses.

It is the collective activity of these electrical pulses across specific groups of neurons that form the representations of different information and experiences within the brain.

Diagram of neuron, featuring a relatively large cell body with a long branching tail extending from it
Neurons are the basic units of the brain.
OpenStax, CC BY-SA

For decades, neuroscientists have thought that the brain learns by changing how neurons are connected to one another. As new information and experiences alter how neurons communicate with each other and change their collective activity patterns, some synaptic connections are made stronger while others are made weaker. This process of synaptic plasticity is what produces representations of new information and experiences within your brain.

In order for your brain to produce the correct representations during learning, however, the right synaptic connections must undergo the right changes at the right time. The “rules” that your brain uses to select which synapses to change during learning – what neuroscientists call the credit assignment problem – have remained largely unclear.

Defining the rules

We decided to monitor the activity of individual synaptic connections within the brain during learning to see whether we could identify activity patterns that determine which connections would get stronger or weaker.

To do this, we genetically encoded biosensors in the neurons of mice that would light up in response to synaptic and neural activity. We monitored this activity in real time as the mice learned a task that involved pressing a lever to a certain position after a sound cue in order to receive water.

We were surprised to find that the synapses on a neuron don’t all follow the same rule. For example, scientists have often thought that neurons follow what are called Hebbian rules, where neurons that consistently fire together, wire together. Instead, we saw that synapses on different locations of dendrites of the same neuron followed different rules to determine whether connections got stronger or weaker. Some synapses adhered to the traditional Hebbian rule where neurons that consistently fire together strengthen their connections. Other synapses did something different and completely independent of the neuron’s activity.

Our findings suggest that neurons, by simultaneously using two different sets of rules for learning across different groups of synapses, rather than a single uniform rule, can more precisely tune the different types of inputs they receive to appropriately represent new information in the brain.

In other words, by following different rules in the process of learning, neurons can multitask and perform multiple functions in parallel.

Future applications

This discovery provides a clearer understanding of how the connections between neurons change during learning. Given that most brain disorders, including degenerative and psychiatric conditions, involve some form of malfunctioning synapses, this has potentially important implications for human health and society.

For example, depression may develop from an excessive weakening of the synaptic connections within certain areas of the brain that make it harder to experience pleasure. By understanding how synaptic plasticity normally operates, scientists may be able to better understand what goes wrong in depression and then develop therapies to more effectively treat it.

Microscopy image of mouse brain cross-section with lower middle-half dusted green
Changes to connections in the amygdala – colored green – are implicated in depression.
William J. Giardino/Luis de Lecea Lab/Stanford University via NIH/Flickr, CC BY-NC

These findings may also have implications for artificial intelligence. The artificial neural networks underlying AI have largely been inspired by how the brain works. However, the learning rules researchers use to update the connections within the networks and train the models are usually uniform and also not biologically plausible. Our research may provide insights into how to develop more biologically realistic AI models that are more efficient, have better performance, or both.

There is still a long way to go before we can use this information to develop new therapies for human brain disorders. While we found that synaptic connections on different groups of dendrites use different learning rules, we don’t know exactly why or how. In addition, while the ability of neurons to simultaneously use multiple learning methods increases their capacity to encode information, what other properties this may give them isn’t yet clear.

Future research will hopefully answer these questions and further our understanding of how the brain learns.The Conversation

William Wright, Postdoctoral Scholar in Neurobiology, University of California, San Diego and Takaki Komiyama, Professor of Neurobiology, University of California, San Diego

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